Where am I supposed to go? Where was I supposed to know? • Violet Indiana • get lost in questions • more quotes
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visualization + math

π Day 2026 Art Posters - Art for the 5%
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
▲ 2026 π DAY | Art for the 5%: digits of `\pi` hidden in plain view. Here, the symbol `\pi` is encoded. (explore the art, BUY ARTWORK)

π Day 2026 Art Posters - Art for the 5%
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
▲ 2026 π DAY | Art for the 5%: digits of `\pi` hidden in plain view. Here the first 9 digits of `\pi` (314 159 265) are encoded. (explore the art, BUY ARTWORK)

`\pi` Day 2017 Art Posters - Star charts and extinct animals and plants


Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2026 π DAY | Art for the 5%.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2025 π DAY | TTCAGT: A sequence of digits.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2024 π DAY | Explore the garden of digits.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2023 π DAY | Repeated sequence


Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2022 π DAY | three one four: a number of digits

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2021 π DAY | Good things grow for those who wait.' edition.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2020 π DAY | The piku.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2019 π DAY | Hundreds of digits, hundreds of languages and a special kids' edition.


Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2018 π DAY | Street maps to new destinations.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2017 π DAY | Imagine the sky in a new way.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2016 π APPROXIMATION DAY | What would happen if about right was right.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2016 π DAY | These digits really fall for each other.


Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2015 π DAY | A transcendental experience.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2014 π APPROXIMATION DAY | Spirals into roughness.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2014 π DAY | Hypnotizes you into looking.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2014 π DAY | Come into the fold.


Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2013 π DAY | Where it started.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ CIRCULAR π ART | And other distractions.

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Most of the art is available for purchase as framed prints and, yes, even pillows. Sleep's never been more important — I take custom requests.

Caelum non animum mutant qui trans mare currunt.
—Horace

This year: creatures that don't exist, but once did, in the skies.

This year's `\pi` day song is Exploration by Karminsky Experience Inc. Why? Because "you never know what you'll find on an exploration".

If you like space, you'll love my the 12,000 billion light-year map of clusters, superclusters and voids. Find the biggest nothings in Boötes and Eridanus.The largest map there is shows the location of voids and galaxy superclusters in our visible universe.
If you like space, you'll love my the 12,000 billion light-year map of clusters, superclusters and voids. Find the biggest nothings in Boötes and Eridanus.The largest map there is shows the location of voids and galaxy superclusters in our visible universe.

create myths and contribute!

Want to contribute to the mythology behind the constellations in the `\pi` in the sky? Many already have a story, but others still need one. Please submit your stories!

This year I wanted to something more than visuals. Space is vast, so let's fill it with words.

I asked my good friend and poet, Paolo Marcazzan, to collaborate. I described the idea for the art—a universe of stars based on `\pi` and the extinct creatures that live within it—and asked him to find the matching words.

And they could not have been more perfect.




harken to my anger, mother Nyx, for the deceptions of the gods —Aeschylus, Eumenides It’s not so much stifled intent but tussle and fracas in the backstage of the heart spoken in privatives and the high tone of failed mending. Says there is nothing to see and you are seeing it. A truth that likes it here in the caul of light swallowed and us locked in probability or antecedent. Where this run to untold receding and dispersed signature ends in parallels denied l’amor che move il sole e l’altre stelle or silenced music that is number on a brim of echo, capsized chamber drawn into our constellation, and cooling.

—Paolo Marcazzan




author's note

The poem situates the dark as a place for contention and ongoing confrontation. Whether in the recesses of space or heart, the poem probes the territory of distance, absence, uncertainty and muteness. It considers the relational as default positioning of existence (earthly, universal), and that which remains unmet within that context.

Life in its dimension of cross-grained, often broken linearity is juxtaposed with a quote form Dante that references instead his vision of sidereal circularity as the benign force that moves all things in the universe. For the earthbound, the questions and concerns remain those of identity, passage, escape from transiency, and slow tempering of hope.

news + thoughts

Chromosomes — music, genomes, split-flaps

Wed 14-10-2026

A short electronic music concert based on structures of chromosomes 21, Y and 1.

Each track uses a microtonal scale derived from the cytogenetic band positions of the chromosome. Rhythms are based on relative lengths of cytogenetic bands.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ CHROMOSOMES | Genomes, split-flaps, music. (watch)
music
Gregory Coles
voice
Hannah Iqbal
concept & animation
Martin Krzywinski
thanks to
John Dupuis

Consequences of missing data

Fri 04-09-2026

Either I've been missing something or nothing has been going on. —Karen Elizabeth Gordon

Missing data are everywhere. Subjects may decline to participate in a survey or fail to answer sensitive questions. A cell culture might fail due to contamination. Instrument failures or mishandling of a sample may lead to missing observations. But why are missing data a problem?

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ Nature Methods Points of Significance column: Consequences of missing data. (read)

This month, we begin a series of articles about practical and statistical aspects of missing data. We'll see that missing data can increase variability and introduce bias and we will ask whether anything can be done to mitigate these consequences. It turns out that, in the case where we know nothing about the missing subjects, no mitigation is possible. We must accept higher variability and, if we have a suspicion that the missing subjects aren’t completely random, possible bias as well.

Tanujit Dey, T., Lipsitz, S.R., Fitzmaurice, G., Krzywinski, M. & Altman, N. (2026) Points of significance: Consequences of missing data. Nat. Methods 23:1661–1663.

Double Robustness

Mon 04-05-2026

It is not certain that everything is uncertain. —Blaise Pascal

We have already explored how we can mitigate bias caused by confounding variables in observational studies using propensity score (PS) matching (PSM) and propensity score weighting (PSW). However, any statistical model is only as good as its assumptions and, if it is specified incorrectly, it can itself produce biased estimates of the treatment effect.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ Nature Methods Points of Significance column: Double Robustness. (read)

This month, we explore double robustness, a powerful statistical concept that provides a valuable “safety net” against the risk of an incorrect model. It offers two opportunities, instead of just one, to obtain a valid estimate of the treatment effect — making it possible to draw credible causal inferences from observational data without having to depend on a single set of modeling assumptions.

Kurz, C.F., Krzywinski, M. & Altman, N. (2026) Points of significance: Double Robustness. Nat. Methods 23:868–869.

Nature Biotechnology cover

Thu 23-04-2026

My cover design on the 7 April 2026 Nature Biotechnology issue shows the dendrogram that represents a cluster of uniquely expressed (or downregulated) genes in human naive stem cells induced from such cells. Within each dendrogram block, the genomic barcode sequence (sampled from Supplementary Table 1) is depicted with a Code 39 barcode. The highlighted barcode is one of those used for cell isolation.

Ishiguro S. et al. A multi-kingdom genetic barcoding system for precise clone isolation (2026) Nature Biotechnology 44:616–629.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ My Nature Biotechnology phylogenetic tree cover (volume 44, issue 4, 7 April 2026). (more)

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ A catalogue of my journal and magazine cover designs. (more)

Happy 2026 π Day—
Art for the 5%

Fri 13-03-2026

Celebrate π Day (March 14th) and enjoy the art — but only if you're part of the 5%.

Go ahead, see what you can't see.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ 2026 π DAY | Art for the 5%. Shown in the style of Ishihara color test plates, the art is visible only to those with colour blindness. (details)

Ishihara's Tests for Colour Deficiency

Sun 08-03-2026

Authentic and accurate images of Ishihara's test plates photographed (and lovingly color-corrected) from the 38-plate Ishihara's Tests for Colour Deficiency.

I also provide the position, size, and color of each circle on each test plate.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ ISHIHARA'S TEST PLATE 6 | This plate is part of the set of transformation plates. If you see 5, you're ok. If you see 2, you're not. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
▲ ISHIHARA'S TEST PLATE 18 | This plate is part of the set of mysterious hidden plates. If you don't see anything, you're ok. If you see 5, you're not. (details)
Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences Centre ⊂ PHSA
Google whack “vicissitudinal corporealization”