Creating new words is fun. It exercises the mind and adds a playful dimension to prosaic speech, without succumbing to bombast associated with deployment of arcane (and often lengthy) words.
When one's own neologisms are heard in use by other people, it also exercises the ego.
circos plot
com·pure
culturally inconversible
de·pen·ders
ee spammings
ex·ist·angs·ty
fez·day
hil·ber·ton·ian
hive panel
hive plot
in·con·ver·si·ble
meta·om·ome
mys·ti·fic
nay·the·ism
nay·the·ist
nes
neu·ro·ter·ror
neu·ro·ter·ror·ism
new·grade
no·ward
non·post·er
old·grade
om·ome
ome·om·ics
omic·so·phy
over
pid·dle
port knocking
post·pe·ti·zer
pre·grat·ul·ate
pre·kfast
pre·nop·sis
pre·pe·ti·zer
quin·ty
ratio hive
spammings
sus·ci·tate
un·app·rop·ri·ate
1a circularly arranged visualization created using Circos
2any circular visualization with concentric tracks, and especially those using lines or curves connecting points on the circumference
usage of circos plot: "Genome visualization without Circos is like a fish with a bicycle." origin of circos plot: Krzywinski, M. et al. Circos: an Information Aesthetic for Comparative Genomics. Genome Res (2009) 19:1639-16451having desirable qualities, often emphasizing visual qualities, so overly maximized as to be disfunctional or unuseable
2perfectly secure, but practically unusable, by virtue of physical and electronic isolation
3anything that is only great on paper
usage of compure: "The IT department built us a compure network. Unfortunately, nobody can log on." usage of compure: "The apartment was compure—easy on the eyes but we couldn't figure out how to open the cupboards." usage of compure: "Beautiful and dumb, she was truly compure." origin of compure: computer + pure1a statement which is not strictly inconversible, but due to cultural or social constraints and customs, is practically so because uttering its converse would invite disgrace
usage of culturally inconversible: "Politicians habitually employ cultural inconversibles to position themselves safely in the eyes of the public." example of culturally inconversible: "Men and women should be treated equally." see also: inconversible1suspenders, discreetly worn under clothing, designed to hold up adult incontinence briefs or any other pads, guards and absorbency products
2suspenders worn under clothing
usage of dependers: "Bob's dependers ensured him with not only peace of mind but also a snug and comfortable fit." origin of dependers: Depend + suspenders1spam reformatted to the style of the poet ee cummings
2a specific instance of spammings
usage of ee spammings: "ee spammings extract a useful dimension from unsolicited communication." example of ee spammings: "please reply / me back i have / something to tell / you (inmportant)" origin of ee spammings: spam + ee cummings see also: spammings1characterized by existential angst, in particular to a small degree
2slightly miffed at the apparent lack of purpose of life and direction of the expanding universe
usage of existangsty: "That cosmology video made me existangsty." origin of existangsty: existential + angst1an occasion, time or day of celebration associated with specific rituals and/or dress, whose origins have been forgotten, with time but usually purposefully, because they harken to a time that was unprosperous, calamitous or embarrassing.
2an unfortunate event whose memory is purposefully perceived as positive to avoid embarrassment or conflict
usage of fezday: "They celebrated fezday, like it was a good thing." usage of fezday: "Nobody could remember the origins of fezday, but everyone always had a good time." usage of fezday: "You couldn't tell the celebrants they looked ridiculous at the risk of incuring their wrath, which always seemed close to the surface." usage of fezday: "Let's have a fezday with this." origin of fezday: fez + day. Based on the legendary account of a long-fought battle which ended in a humiliating defeat, made visibly worse by the victor demanding that the losing side wear a fez each year in shame. Many years passed. Over time the losing side's embarrassment and resentment grew. The fez embodied their humiliation and loss, both intolerable. Eventually, the original reason for the fez was struck from historical record. The day was turned into a celebration of independence and identity. The fez became a national symbol and was widely worn.1a creature that lives on 3 adjacent orders of the Hilbert curve.
2a creature of one of the 14 classes of Hilbertonians: alien, voyager, crossfit, breaker, spider, sentinel, dasher, creeper, poser, screamer, chopper, veggie, fez and peep.
usage of hilbertonian: "I think this Hilbertonian is a creeper." example of hilbertonian: "Classification of Hilbertonians." origin of hilbertonian: from Hilbert curve1a matrix of hive plots presenting multiple independent visual signatures of a network
usage of hive panel: "The hive panels of these two networks helped me see minor differences in structure I would have normally missed." see also: hive plot, ratio hive1a network visualization method which assigns and positions nodes on linear axes using rules based on structural properties of the network
2periodic parallel axis plot in which the axes are arranged radially, like in a radar plot
usage of hive plot: "Hive plots create rational network visualizations that can be easily interpreted and compared." see also: hive panel, ratio hive1typically refering to a statement, something whose converse is illogical or senseless, thereby diluting the substance and information content of the original.
2anything whose converse is senseless, either by definition or logic
usage of inconversible: "He concealed the lack of substance in his delivery by long inconversible statements" example of inconversible: "I like to have fun." origin of inconversible: in- (non) and conversible see also: culturally inconversible1The collection of annotations, such as user comments, literature citations and functional and structural interpretations, of an omome.
usage of metaomome: "Many centers lack the computational resources to study the entire omome and, instead, focus on metaomomics — the study of its annotations, a more tractable challenge." example of metaomome: "Ome, the Sound of the Scientific Universe Expanding in the NYT" origin of metaomome: meta + omeome see also: omeomics, omome1terrific, but for unknown or mysterious reasons
2strangely wonderful
usage of mystific: "Waiter, this meal is mystific. Can you give me a hint?" origin of mystific: mysterious + terrific1a belief system in which it is taken on faith that God does not exist.
usage of naytheism: "My position of naytheism is unassailable by the theists because it uses the same modes of reasoning." origin of naytheism: nay + theism see also: naytheist1a person who takes it on faith that God doesn't exist.
usage of naytheist: "As a naytheist, I count on my faith to support my views." origin of naytheist: nay + theism see also: naytheism1typically to a yes or no question, a response suggesting that both answers hold equal merit in such balance that deciding is difficult and potentially impossible; distinguished from maybe in that nes does not require the speaker to ever reach a decision, nor communicate their intention to do so.
usage of nes: "When John asked me on a date, I said 'nes'." origin of nes: no + yes; counterparts in other languages may exist, such as noui in French (non/oui), jain in German (ja/nein), and niak in Polish (nie/tak) — notice that the order of the words can vary in different languages to create the more appealing combination1fear elicited by direct chemical or electrical stimulation of the brain, without an external fearsome stimulus
usage of neuroterror: "After the development of aerosolized fear-causing neuromodulators, the courts had a difficult time in determining whether their use was captured by the laws governing the classical definition of terror." see also: neuroterrorism1use of neuroterror for coersion or control
usage of neuroterrorism: "It was unclear whether last month's incident was an act of neuroterror or simply spontaneous mass panic." see also: neuroterror1replace something with a newer thing
usage of newgrade: "I had to newgrade my phone—they sure don't make things like they used to!" usage of newgrade: "This phone oldgrade is definitely a downgrade." origin of newgrade: Provides the equivalent of downgrade and upgrade, but relative to age and not function or quality. see also: oldgrade1without direction or intent
usage of noward: "Your focus is pointing noward." origin of noward: As an analogy to forward, onward and backward, noward is the directional equivalent of the positional nowhere. Words relating to movement with a specific destination in mind would use nowhere (i.e. no place), those hinged on direction would use noward (i.e. no direction).1the guilty's garbage can
usage of nonposter: "Looking at the contents of your nonposter, I see that you are not engaged in environmental causes." origin of nonposter: non + composter1replace something with an older thing
usage of oldgrade: "I've oldgraded my car—I love classics." usage of oldgrade: "I decided to upgrade and oldgraded my espresso machine." origin of oldgrade: Provides the equivalent of downgrade and upgrade, but relative to age and not function or quality. see also: newgrade1The collective set of all omics, such as genomics, proteomics, exomics, metabolomics, etc.
example of omome: "Ome, the Sound of the Scientific Universe Expanding in the NYT" origin of omome: omics + -ome see also: metaomeome, omeomics, omicsophy1synonym for omicsophy
example of omeomics: "Ome, the Sound of the Scientific Universe Expanding in the NYT" origin of omeomics: omics + -sophy see also: metaomeome, omicsophy1The study of the collection of omics, the broad fields whose name ends in the omics suffix (commonly found in the biological sciences), such as genomics, proteomics, exomics, metabolomics, etc.
example of omicsophy: "Ome, the Sound of the Scientific Universe Expanding in the NYT" origin of omicsophy: omics + -sophy see also: metaomeome, omeomics, omome1a sleepover, but without sleep, ideally ending in a prekfast.
usage of over: "After last night's over, I was exhausted but happy the next day." see also: prekfast1liquid unit of measure, equivalent to a pinch
2spontaneous urination from a small, typically obnoxious, dog, amidst excitement
3in general, a small amount of any liquid uncontrollably produced
example of piddle: "This Yorkshire pudding recipe calls for a piddle of drippings." origin of piddle: off-label use of piddle1a method in computer security to authenticate a remote host with a server without the use of any open ports
usage of port knocking: "My server cannot be detected by a port scan, but I can still login because I use port knocking." origin of port knocking: Krzywinski, M. Port Knocking: Network authentication across closed ports. SysAdmin Magazine (2003) 12:12-171a small meal ordered after dessert, consumed during examination and settling of the bill
usage of postpetizer: "The desert was delicious but we are still peckish — could you bring us a postpetizer with the bill please?" see also: prepetizer1offer praise in anticipation of success
2offer contratulations before success is achieved
usage of pregratulate: "On my first day of college my parents pregratulated me on my graduation." origin of pregratulate: pre + contratulate see also: prenopsis1a light snack, before breakfast, typically prepared and presented by one's sleep partner and consumed in bed
usage of prekfast: "She was thoughtful to bring me a prekfast after our over." origin of prekfast: pre + breakfast see also: over1a summary, such as of a book, program or event, formed purely on expectation, bias and hope, formulated before the object or event is experienced
usage of prenopsis: "Looking at the book's cover in the store, I quickly formulated a prenopsis which proved suprisingly accurate."1a small meal, typically delivered quickly, ordered after the arrival, but before reading, of the menu, intended to quench the initial hunger until the arrival of the appetizer
usage of prepetizer: "We are starving — could you bring us a prepetizer while we look at the menu?" origin of prepetizer: pre + appetizer similar to: amuse-bouche see also: postpetizer1a person or thing possessing rare or special qualities or traits, thereby potentially embodying the fifth essence
usage of quinty: "This dessert is so divine, as to be almost quinty." origin of quinty: diminutive of quintessential, in a more relaxed use1a hive plot used to visualize ratio quantities between three or more axes, employing stacked ribbons to show the cumulative distribution of values
2periodic stacked bar plot in which the axes are arranged radially, like in a radar plot
usage of ratio hive: "Ratio hives can be used to illustrate differences in composition or structure of various object." see also: hive panel, hive plot1short form of ee spammings
2unsolicited communication reformatted, with poetic license, into a more palatable form
see also: ee spammings1to raise an individual's life energy so far beyond previous highest level as to give the impression of life for the first time
2to animate, energize, or stimulate an entity to a new level of liveliness.
3(figurative) to breate life into, for the first time
usage of suscitate: "Looks like meeting Mary really suscitated John. I've never seen him this alive." origin of suscitate: resuscitate, except without re-, implying that the entity has never livedI don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player
In many experimental designs, we need to keep in mind the possibility of confounding variables, which may give rise to bias in the estimate of the treatment effect.
If the control and experimental groups aren't matched (or, roughly, similar enough), this bias can arise.
Sometimes this can be dealt with by randomizing, which on average can balance this effect out. When randomization is not possible, propensity score matching is an excellent strategy to match control and experimental groups.
Kurz, C.F., Krzywinski, M. & Altman, N. (2024) Points of significance: Propensity score matching. Nat. Methods 21:1770–1772.
We'd like to say a ‘cosmic hello’: mathematics, culture, palaeontology, art and science, and ... human genomes.
All animals are equal, but some animals are more equal than others. —George Orwell
This month, we will illustrate the importance of establishing a baseline performance level.
Baselines are typically generated independently for each dataset using very simple models. Their role is to set the minimum level of acceptable performance and help with comparing relative improvements in performance of other models.
Unfortunately, baselines are often overlooked and, in the presence of a class imbalance, must be established with care.
Megahed, F.M, Chen, Y-J., Jones-Farmer, A., Rigdon, S.E., Krzywinski, M. & Altman, N. (2024) Points of significance: Comparing classifier performance with baselines. Nat. Methods 21:546–548.
Celebrate π Day (March 14th) and dig into the digit garden. Let's grow something.