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fun + Amusement

Dummer - Like Nothing Else / A Hummer Satire

The Dummer project might give you the impression that I don't like Hummers. You'd be right.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
What's after worst? This. (Dummer. Like nothing else.)

The project was well received by The New York Times and very poorly by someone who felt sending me hate mail was a good idea. It was — I loved it.

Other Hummer satires include fuh2.com — there's some hope for us all.


The World's Most Popular Questions

What are the world's most popular questions? After all, what we know defines us as much as what we ask. So, let's look at who we are.

Using Google's autocomplete feature, which suggests the most similar searches to the one you have entered, I maintain a real-time compilation of the most common questions asked by millions of worldwide internet users.

This project (a) yields insight into the zeitgeist and (b) scares me. My reason for fright are questions such as these:

General Issues

How do people do extreme couponing?

Why can't I hold all these limes?

Why do I always feel like murdering everyone?

What's up with the World

Is the world really flat?

is the world being controlled by aliens?

Limits & Desires

What happens if I make a formal commitment to Satan?

Love & Heart

Why is my boyfriend so insecure?

Why is my girlfriend so emotional?

Health

My head is full of pretty lumps.

Pain & Suffering

my elbow is dark and dry

why do I continue to hit myself with a hammer?

when does my head stop growing?

Sizes & Extremes

Who is the most powerful Jedi?

Where is the hardest part of your head?

Religion & Faith

Can Jesus microwave a burrito?

Can I pray with my eyes open?

Should I pray for a husband?

Neologisms - New Words, Much Needed

I like words. The pleasure of effectively using acerebral and defenestrate in the same sentence cannot be understated.

On occassion I found myself in a situation where no word fit, existing or that I know about. Instead of rushing to the dictionary, I decided to make up my own, such as inconversible (a statement without a logical converse), mystific (unexplainably wonderful), postpetizer (course ordered after dessert), prenopsis (a summary of something formulated before it was experienced), suscitate (breathe life into, for the first time), and others.

The current list of my neologisms is circos plot, compure, culturally inconversible, dependers, ee spammings, existangsty, fezday, hilbertonian, hive panel, hive plot, inconversible, metaomome, mystific, naytheism, naytheist, nes, neuroterror, neuroterrorism, newgrade, noward, nonposter, oldgrade, omome, omeomics, omicsophy, over, piddle, port knocking, postpetizer, pregratulate, prekfast, prenopsis, prepetizer, quinty, ratio hive, spammings, suscitate, unappropriate .


HDTR: High Dynamic Time Range Photography - Visualizing the Flow of Time

The HDTR method is a new approach to depicting the passage of time. High Dynamic Time Range (HDTR) images and are a composite of many photos taken over a long period of time, such as a day or even longer. Each part of the HDTR image is sampled from a different photo, either by column or row.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
An HDTR is generated from a set of time-lapse images. Here, a simple HDTR is created from 5 images taken at different times. From each image, a strip representing 20% of the image is extracted and the strips are blended to reduce banding artefacts. (hires)

For example, the left part of the HDTR image might show the scene from 7am and the very right from 8pm, capturing the variation in light across an entire day.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
An HDTR image shows the flow of time across a scene. Here the Vancouver skyline is shown from about 6pm (left) to 9pm (right). (Download)
news + thoughts

Happy 2026 π Day—
Art for the 5%

Fri 13-03-2026

Celebrate π Day (March 14th) and enjoy the art — but only if you're part of the 5%.

Go ahead, see what you can't see.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2026 π DAY | Art for the 5%. Shown in the style of Ishihara color test plates, the art is visible only to those with colour blindness. (details)

Ishihara's Tests for Colour Deficiency

Sun 08-03-2026

Authentic and accurate images of Ishihara's test plates photographed (and lovingly color-corrected) from the 38-plate Ishihara's Tests for Colour Deficiency.

I also provide the position, size, and color of each circle on each test plate.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
ISHIHARA'S TEST PLATE 6 | This plate is part of the set of transformation plates. If you see 5, you're ok. If you see 2, you're not. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
ISHIHARA'S TEST PLATE 18 | This plate is part of the set of mysterious hidden plates. If you don't see anything, you're ok. If you see 5, you're not. (details)

Symmetric alternatives to the ordinary least squares regression

Wed 23-07-2025

What immortal hand or eye, could frame thy fearful symmetry? — William Blake, "The Tyger"

This month, we look at symmetric regression, which, unlike simple linear regression, it is reversible — remaining unaltered when the variables are swapped.

Simple linear regression can summarize the linear relationship between two variables `X` and `Y` — for example, when `Y` is considered the response (dependent) and `X` the predictor (independent) variable.

However, there are times when we are not interested (or able) to distinguish between dependent and independent variables — either because they have the same importance or the same role. This is where symmetric regression can help.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Symmetric alternatives to the ordinary least squares regression. Geometry of quantities minimized in OLS and symmetric regression. OLS minimizes `\Sigma e_y^2` in `Y` ~ `X` and `\Sigma e_x^2` `X` ~ `Y`. Pythagorean regression minimizes AB (magenta). Geometric means regression (GMR) minimizes area of ABP (orange). Orthogonal regression (OR) minimizes HP (blue). (read)

Luca Greco, George Luta, Martin Krzywinski & Naomi Altman (2025) Points of significance: Symmetric alternatives to the ordinary least squares regression. Nat. Methods 22:1610–1612.

Beyond Belief Campaign BRCA Art

Wed 11-06-2025

Fuelled by philanthropy, findings into the workings of BRCA1 and BRCA2 genes have led to groundbreaking research and lifesaving innovations to care for families facing cancer.

This set of 100 one-of-a-kind prints explore the structure of these genes. Each artwork is unique — if you put them all together, you get the full sequence of the BRCA1 and BRCA2 proteins.

Propensity score weighting

Mon 17-03-2025

The needs of the many outweigh the needs of the few. —Mr. Spock (Star Trek II)

This month, we explore a related and powerful technique to address bias: propensity score weighting (PSW), which applies weights to each subject instead of matching (or discarding) them.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score weighting. (read)

Kurz, C.F., Krzywinski, M. & Altman, N. (2025) Points of significance: Propensity score weighting. Nat. Methods 22:638–640.

Happy 2025 π Day—
TTCAGT: a sequence of digits

Thu 13-03-2025

Celebrate π Day (March 14th) and sequence digits like its 1999. Let's call some peaks.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2025 π DAY | TTCAGT: a sequence of digits. The digits of π are encoded into DNA sequence and visualized with Sanger sequencing. (details)
Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentrePHSA
Google whack “vicissitudinal corporealization”
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