On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.
For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!
If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!
Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.
Welcome to this year's celebration of `\pi` and mathematics. Among the chaos of COVID-19, this year `\pi` Day celebrations are short poetic emissions I call “piku”. They are brief pauses for the time.
Start by reading how piku are constructed and then browse submitted piku. Consider participating by submitting your own piku. All you need is a pen and a few (small) words. Very therapeutic.
But if the words here don't help, immerse yourself in my coronavirus art. It's quite catching.
If you enjoy poetry and words, see how I convert spam into poems in the style of ee cummings and if you like to see words arrange on page, look through my typographic art.
What does this poem have to do with `\pi` day?
Or this one?
These are all nku (details and definitions). Like a haiku, an nku is a poem whose structure (line and syllable count) is constrained by the digits in some number `n`.
The first poem above is a piku (`\pi`ku, パイク), based on the first three digits of `\pi`. The second poem above is the nku for the date of this year's celebration 14032020.
Even `\pi` approximation day 22/7 has its own nku.
Those that believe in the power of the Tau manifesto (`\tau = 2 \pi`) can create “tauku”.
I celebrate Tau day with equal, not double, enthusiasm and have made Tau day art.
If you would like to contribute to this year's piku celebration, email me a piku with "PIKU:" in subject line. Or, tweet it with the #piku hashtag.
My cover design on the 7 April 2026 Nature Biotechnology issue shows the dendrogram that represents a cluster of uniquely expressed (or downregulated) genes in human naive stem cells induced from such cells. Within each dendrogram block, the genomic barcode sequence (sampled from Supplementary Table 1) is depicted with a Code 39 barcode. The highlighted barcode is one of those used for cell isolation.
Ishiguro S. et al. A multi-kingdom genetic barcoding system for precise clone isolation (2026) Nature Biotechnology 44:616–629.
Browse my gallery of cover designs.
Celebrate π Day (March 14th) and enjoy the art — but only if you're part of the 5%.
Go ahead, see what you can't see.
Authentic and accurate images of Ishihara's test plates photographed (and lovingly color-corrected) from the 38-plate Ishihara's Tests for Colour Deficiency.
I also provide the position, size, and color of each circle on each test plate.
What immortal hand or eye, could frame thy fearful symmetry? — William Blake, "The Tyger"
This month, we look at symmetric regression, which, unlike simple linear regression, it is reversible — remaining unaltered when the variables are swapped.
Simple linear regression can summarize the linear relationship between two variables `X` and `Y` — for example, when `Y` is considered the response (dependent) and `X` the predictor (independent) variable.
However, there are times when we are not interested (or able) to distinguish between dependent and independent variables — either because they have the same importance or the same role. This is where symmetric regression can help.
Luca Greco, George Luta, Martin Krzywinski & Naomi Altman (2025) Points of significance: Symmetric alternatives to the ordinary least squares regression. Nat. Methods 22:1610–1612.
Fuelled by philanthropy, findings into the workings of BRCA1 and BRCA2 genes have led to groundbreaking research and lifesaving innovations to care for families facing cancer.
This set of 100 one-of-a-kind prints explore the structure of these genes. Each artwork is unique — if you put them all together, you get the full sequence of the BRCA1 and BRCA2 proteins.
The needs of the many outweigh the needs of the few. —Mr. Spock (Star Trek II)
This month, we explore a related and powerful technique to address bias: propensity score weighting (PSW), which applies weights to each subject instead of matching (or discarding) them.
Kurz, C.F., Krzywinski, M. & Altman, N. (2025) Points of significance: Propensity score weighting. Nat. Methods 22:638–640.