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Without an after or a when.Papercut feat. Maiken Sundbycan you hear the rain?more quotes
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Song of the Eastern Towhee (Pipilo erythrophthalmus) by Martin Krzywinski
VISIONS OF TYPE | Put my typographical posters on your wall. (buy artwork / see all my art)
The 2020 π Day art celebrates the digits of π with piku (パイク) — poetry inspired by haiku. They serve as the form for The Outbreak Poems. On our 2022 Pi Day album "three one four: a number of notes", a piku accompanies each track.
My SnellenMK font adds lowercase and punctuation to the traditional Snellen design.

Visions of Type

1 · Typography and bird songs

If you live in a city, birds are essentially the only wildlife that you meet during your day.

Depending on where you live, you might come several species without even trying. In Vancouver, on a 10 minute walk around my house, I have a good chance to see rock doves (pigeons), crows, mallars, wigeons, hooded mergansers (if I'm lucky), common starlings, house sparrows (sigh), house finches, song sparrows, red-winged black birds, white-crowned sparrows, bushtits, black-capped chickadees, northern flickers, great blue herons, and the mother-of-all-honkers: Canada geese.

Birds and letters are everywhere—art of nature and man.

Letter forms, on the other hand, are the art that is also everywhere. Every typeface is an artistic expression.

Regardless where you live, sadly, you are likely to come across mutants like Comic Sans, Arial and Times New Roman — odious creatures from the shallows. Try to find Gotham, Gill Sans, Frutiger, or Garamond.

2 · The Spectrogram

Bird songs can be visualized with a spectrogram — a visualization of the frequency components (vertical axis) in the call as a function of time (horizontal axis).

For example, below is a crop of a recording of the American goldfinch, who eats a potato chip in about 0.5 seconds. And when in flight, he has it with dip.


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The spectrogram of the American goldfinch, who eats a potato chip in about 0.5 seconds. (Macaulay Library asset 94457)

The full recording from the Cornell Lab Macaulay Library is shown below.

Spectrograms give us detailed insight into the fine structure of a vocalization. For example, the black-capped chicadee's “fee-bee” (or cheeseburger) actually has a very short pause (about 50 ms) in the “bee”, making it more of a “be-e”. Below is a recording of this call.

One of my favourite bird sounds is the “sawing machine” of the marsh wren. They often hide in tall reeds around ponds and lakes, making them hard to spot — by eye, but not by ear!

3 · Learning bird songs

Mnemonics of bird songs help you remember the call and recognize the bird. It's so much easier to think "Quick, three beers!" — the call of the Olive-sided flycatcher — rather than "Chirp, chirp, chirp."

The mnemonic captures the cadence and repetition scheme of the song. For example, if you listen to the white-throated sparrow you can't help but think that this little guy is trying to tell us something.

4 · The mnemonics

French Zonotrichia albicollis: Baisse ta jupe, Philomène, Philomène, Philomène. How differently we hear!
—Madelaine Lemieux (via Twitter)

Potato chip!
American Goldfinch (Spinus tristis)

Here here. Come right here, dear.
Baltimore Oriole (Icterus galbula)

Who cooks for you?
Barred Owl (Strix varia)

Here sweetie.
Black-capped Chickadee (Poecile atricapillus)

Trees, trees, murmuring trees.
Black-throated Green Warbler (Setophaga virens)

Drink your tea.
Eastern Towhee (Pipilo erythrophthalmus)

Are you awake? Me too.
Great Horned Owl (Bubo virginianus)

Qu'est-ce qu-il dit?
Great Kiskadee (Pitangus sulphuratus)

Fire fire. Where where? Here here! See it, see it.
Indigo Bunting (Passerina cyanea)

Clear. Wick, wick, wick.
Northern Flicker (Colaptes auratus)

Quick, three beers!
Olive-sided Flycatcher (Contopus cooperi)

Where are you? Here I am.
Red-eyed Vireo (Vireo olivaceus)

Chubby chubby cheeks. Chubby cheeks.
Ruby-crowned Kinglet (Regulus calendula)

See me, pretty, pretty me.
White-crowned Sparrow (Zonotrichia leucophrys)

Dear sweet Canada Canada Canada.
White-throated Sparrow (Zonotrichia albicollis)

5 · The posters

buy artwork Song of the Indigo Bunting (Passerina cyanea) by Martin Krzywinski
FIRE FIRE. WHERE WHERE? HERE HERE! SEE IT, SEE IT | Song of the Indigo Bunting. (buy artwork / see all my art)

If you love birds and typography, these posters are for you. The mnemonic for the bird's song is presented on a background that proportionally presents the bird's plumage colors.

5.1 · Poster sets

Some posters create natural sets.

5.2 · Individual posters

And if you explore the posters, you just might find the bird too.


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
POTATO CHIP! | Song of the American Goldfinch (Spinus tristis) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
HERE HERE. COME RIGHT HERE, DEAR. | Song of the Baltimore Oriole (Icterus galbula) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
WHO COOKS FOR YOU? | Song of the Barred Owl (Strix varia) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
HERE SWEETIE. | Song of the Black-capped Chickadee (Poecile atricapillus) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
TREES, TREES, MURMURING TREES. | Song of the Black-throated Green Warbler (Setophaga virens) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
DRINK YOUR TEA. | Song of the Eastern Towhee (Pipilo erythrophthalmus) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
ARE YOU AWAKE? ME TOO. | Song of the Great Horned Owl (Bubo virginianus) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
QU'EST-CE QU-IL DIT? | Song of the Great Kiskadee (Pitangus sulphuratus) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
FIRE FIRE. WHERE WHERE? HERE HERE! SEE IT, SEE IT. | Song of the Indigo Bunting (Passerina cyanea) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
CLEAR. WICK, WICK, WICK. | Song of the Northern Flicker (Colaptes auratus) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
QUICK, THREE BEERS! | Song of the Olive-sided Flycatcher (Contopus cooperi) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
WHERE ARE YOU? HERE I AM. | Song of the Red-eyed Vireo (Vireo olivaceus) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
CHUBBY CHUBBY CHEEKS. CHUBBY CHEEKS. | Song of the Ruby-crowned Kinglet (Regulus calendula) (BUY ARTWORK)

Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
SEE ME, PRETTY, PRETTY ME. | Song of the White-crowned Sparrow (Zonotrichia leucophrys) (BUY ARTWORK)


Typographical posters of bird songs
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
DEAR SWEET CANADA CANADA CANADA. | Song of the White-throated Sparrow (Zonotrichia albicollis) (BUY ARTWORK)
news + thoughts

Happy 2025 π Day—
TTCAGT: a sequence of digits

Thu 13-03-2025

Celebrate π Day (March 14th) and sequence digits like its 1999. Let's call some peaks.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2025 π DAY | TTCAGT: a sequence of digits. The digits of π are encoded into DNA sequence and visualized with Sanger sequencing. (details)

Crafting 10 Years of Statistics Explanations: Points of Significance

Sun 09-03-2025

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

Points of Significance is an ongoing series of short articles about statistics in Nature Methods that started in 2013. Its aim is to provide clear explanations of essential concepts in statistics for a nonspecialist audience. The articles favor heuristic explanations and make extensive use of simulated examples and graphical explanations, while maintaining mathematical rigor.

Topics range from basic, but often misunderstood, such as uncertainty and P-values, to relatively advanced, but often neglected, such as the error-in-variables problem and the curse of dimensionality. More recent articles have focused on timely topics such as modeling of epidemics, machine learning, and neural networks.

In this article, we discuss the evolution of topics and details behind some of the story arcs, our approach to crafting statistical explanations and narratives, and our use of figures and numerical simulations as props for building understanding.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Crafting 10 Years of Statistics Explanations: Points of Significance. (read)

Altman, N. & Krzywinski, M. (2025) Crafting 10 Years of Statistics Explanations: Points of Significance. Annual Review of Statistics and Its Application 12:69–87.

Propensity score matching

Mon 16-09-2024

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

In many experimental designs, we need to keep in mind the possibility of confounding variables, which may give rise to bias in the estimate of the treatment effect.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score matching. (read)

If the control and experimental groups aren't matched (or, roughly, similar enough), this bias can arise.

Sometimes this can be dealt with by randomizing, which on average can balance this effect out. When randomization is not possible, propensity score matching is an excellent strategy to match control and experimental groups.

Kurz, C.F., Krzywinski, M. & Altman, N. (2024) Points of significance: Propensity score matching. Nat. Methods 21:1770–1772.

Understanding p-values and significance

Tue 24-09-2024

P-values combined with estimates of effect size are used to assess the importance of experimental results. However, their interpretation can be invalidated by selection bias when testing multiple hypotheses, fitting multiple models or even informally selecting results that seem interesting after observing the data.

We offer an introduction to principled uses of p-values (targeted at the non-specialist) and identify questionable practices to be avoided.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Understanding p-values and significance. (read)

Altman, N. & Krzywinski, M. (2024) Understanding p-values and significance. Laboratory Animals 58:443–446.

Depicting variability and uncertainty using intervals and error bars

Thu 05-09-2024

Variability is inherent in most biological systems due to differences among members of the population. Two types of variation are commonly observed in studies: differences among samples and the “error” in estimating a population parameter (e.g. mean) from a sample. While these concepts are fundamentally very different, the associated variation is often expressed using similar notation—an interval that represents a range of values with a lower and upper bound.

In this article we discuss how common intervals are used (and misused).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Depicting variability and uncertainty using intervals and error bars. (read)

Altman, N. & Krzywinski, M. (2024) Depicting variability and uncertainty using intervals and error bars. Laboratory Animals 58:453–456.

Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA
Google whack “vicissitudinal corporealization”
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