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π Day 2025 Art Posters - TTCAGT: a sequence of digits
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
2025 π DAY | TTCAGT: A sequence of digits. 768 digits of `\pi` as a Sanger sequencing trace of 1,536 peaks. Decode the sequence (BUY ARTWORK)

`\pi` Day 2018 Art Posters - Stitched city road maps from around the world


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2024 π DAY | Explore the garden of digits.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2023 π DAY | Repeated sequence

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2022 π DAY | three one four: a number of digits

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2021 π DAY | Good things grow for those who wait.' edition.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2020 π DAY | The piku.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 π DAY | Hundreds of digits, hundreds of languages and a special kids' edition.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 π DAY | Street maps to new destinations.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 π DAY | Imagine the sky in a new way.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 π APPROXIMATION DAY | What would happen if about right was right.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 π DAY | These digits really fall for each other.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 π DAY | A transcendental experience.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π APPROXIMATION DAY | Spirals into roughness.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π DAY | Hypnotizes you into looking.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π DAY | Come into the fold.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 π DAY | Where it started.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
CIRCULAR π ART | And other distractions.

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Most of the art is available for purchase as framed prints and, yes, even pillows. Sleep's never been more important — I take custom requests.

And if you've got to sleep a moment on the road
I will steer for you
And if you want to work the street alone
I'll disappear for you
—Leonard Cohen (I'm Your Man)

This year's is the 30th anniversary of `\pi` day. The theme of the art is bridging the world and making friends. So myself I again team up with my long-time friend and collaborator Jake Lever. I worled with Jake on the snowflake catalogue, where we build a world of flakes.

And so, this year we also build a world. We start with all the roads in the world and stitch them together in brand new ways. And if you walk more than 1 km in this world, you'll likely to be transported somewhere completely different.

This year's `\pi` day song is Trance Groove: Paris. Why? Because it's worth to go to new places—real or imagined.

The input data set to the art are all the roads in the world, as obtained from Open Street Map.

Road segments between intersections are represented by polylines and ends at intersections are snapped together to coincide with a resolution of 5–10 meters.

There are 108,366,429 polylines and together they span about 39,930,000 km.

extracting cities

We took 44 cities and sampled a square patch of 0.6 × 0.6 degrees of roads from the data set centered on the longitude and latitude coordinates below. This roughly corresponds to a square of 65 km × 65 km.

These center coordinates might be slightly different from the canonical ones associated with a city—I used Google Maps to center the coordinates on what I felt was a useful center for sampling streets. Below are these coordinates along with the number of polylines extracted.

           CITY    LATITUDE      LONGITUDE  POLYLINES
--------------- ------------ -------------  ---------
      amsterdam  52.38179720    4.90840330   98,965
        bangkok  13.72635950  100.53609560  154,348
      barcelona  41.38759720    2.17333560   86,575
        beijing  39.90487690  116.39331750   49,867
         berlin  52.51864170   13.40732310   64,336
   buenos_aires -34.61566250  -58.50333750  267,432
          cairo  30.05371250   31.23528970  108,524
     copenhagen  55.67346250   12.58781160   45,025
           doha  25.28233490   51.53479620   50,458
         dublin  53.34316360   -6.24433520   44,109
      edinburgh  55.94884870   -3.18828100   34,211
      hong_kong  22.31338230  114.16994610   36,329
       istanbul  41.03592820   28.98158110  190,938
        jakarta  -6.21858830  106.85252890  253,211
   johannesburg -26.20653880   28.05113830  128,840
         lisbon  38.73064000   -9.13667460   98,118
         london  51.50838960   -0.08585320  169,164
    los_angeles  34.04362360 -118.24505510  193,899
         madrid  40.41671290   -3.70329570  112,495
      marrakesh  31.63192610   -7.98895890   17,442
      melbourne -37.88286720  145.11800540  140,817
    mexico_city  19.39741470  -99.15827060  273,477
         moscow  55.75202630   37.61531070   40,043
         mumbai  19.18775070   72.97777590   65,316
        nairobi  -1.28718700   36.83157870   31,317
      new_delhi  28.61245350   77.21369970  262,503
       new_york  40.72187290  -73.92426750  199,652
           nice  43.70006260    7.26974590   25,564
          osaka  34.66944300  135.49965600  376,652
          paris  48.85837360    2.29229260  175,028
         prague  50.08022370   14.43002100   58,659
           rome  41.89659480   12.49983650   81,370
  san_francisco  37.77526950 -122.40966350   82,462
      sao_paulo -23.57343700  -46.63341590  267,742
          seoul  37.54869140  126.99479350  169,593
       shanghai  31.22590500  121.47386710   50,036
  st_petersburg  59.93029690   30.33955910   31,186
      stockholm  59.32318770   18.07408060   48,321
         sydney -33.86772020  151.20734660   76,820
          tokyo  35.69220740  139.75613010  694,893
        toronto  43.66328030  -79.38932030   73,173
      vancouver  49.25782630 -123.19394300   34,081
         vienna  48.20740250   16.37336040   53,669
         warsaw  52.23101840   21.01639680   54,870

Each city's road coordinates were then transformed using the equirectangular projection to make the distance between longitude meridians constant with latitude. This was done by $$ \phi' \leftarrow \phi - \text{avg}(\phi) $$ $$ \lambda' \leftarrow (\lambda - avg(\lambda)) \text{cos} (avg(\phi)) $$

where `\phi` is the latitude and `\lambda` is the longitude. The average is taken over the patch of roads extracted for the city. For all steps below these transformed coordinates were used.

copenhagen

Let's look at one city—Copenhagen—to get a feel for the data set.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The roads in and around Copenhagen. (zoom)

In the zoom crop below, you can see the intersections (dots) and the individual polylines that connect the intersections.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Downtown Copenhagen. (zoom)

Zooming in even more you can see the Christiansborg Slot, one of the Danish Palaces and the seat of the Danish Parliament (corresponding Google Map view).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
In and around Christiansborg Slot (red dot) in downtown Copenhagen. (zoom)

creating city strips

City strips were created by sampling patches of 0.015 × 0.015 degrees (after transformation). This corresponds roughly to 1.7 km.

For each position in the strip, patches were sampled in order of the digits of `\pi` only if the number of polylines in the was `40d \le N < 40(d+1)-1` where `d` is the digit of `\pi`. Patches for `d=9` only need to have `360 \le N` polylines.

For example, the first patch is assigned to `d=3` and it must have `120 \le N < 159` polylines. The second patch is sampled so that its density is `40 \le N < 79` because it is associated with the next digit, `d=1`.

Further selection on acceptable patches is performed so that the streets line up with the previous patch. Minor local adjustments and stitching are performed to make the join appear seamless.

Below is an example of a set of city strips for Amsterdam, Bangkok, Beijing, Berlin, Copenhagen, Edinburgh, Hong Kong, Johannesburg, Marrakesh and Melbourne.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Moscow, Mumbai, Nairobi, New Delhi, Nice, Prague, Rome, Stockholm, Vancouver and Warsaw. (BUY ARTWORK)

Below I zoom in on a portion of the city strips above to show the result of the stitching—individual street patches are outlined in blue squares.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Close-up of stitched streets in a city strip.

It's interesting to see that some patches (e.g. 4th one on the bottom strip, which is Copenhagen) don't necessarily have roads that across the patch horizontally.

creating world patches

World patches are a two-dimension version of city strips but they use more than one city.

Patches are sampled from cities based on the order of the digits of `\pi`, as arranged on a 6 × 6 grid. For example, the first row of patches corresponds to 314159 and the second 265358. Each digit is assigned to a city from which the corresponding patch is sampled.

As for city strips, patches are selected only if they align with previous patches. This is now trickier to do in two-dimensions because we must match a selected patch with up to two other patches already placed.

Unlike for city strips, there is no selection made for street density.

Below is a world patch using the following digit-to-city assignment: 0:Amsterdam, 1:Doha, 2:Marrakesh, 3:Mumbai, 4:Nairobi, 5:Rome, 6:San Francisco, 7:Seoul, 8:Shanghai and 9:Vancouver.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Doha, Marrakesh, Mumbai, Nairobi, Rome, San Francisco, Seoul, Shanghai and Vancouver (BUY ARTWORK)

Below I zoom in on patches in the center of the image and show the cities from which the patches were sampled.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Close-up of stitched streets in a world patch.
news + thoughts

Beyond Belief Campaign BRCA Art

Wed 11-06-2025

Fuelled by philanthropy, findings into the workings of BRCA1 and BRCA2 genes have led to groundbreaking research and lifesaving innovations to care for families facing cancer.

This set of 100 one-of-a-kind prints explore the structure of these genes. Each artwork is unique — if you put them all together, you get the full sequence of the BRCA1 and BRCA2 proteins.

Propensity score weighting

Mon 17-03-2025

The needs of the many outweigh the needs of the few. —Mr. Spock (Star Trek II)

This month, we explore a related and powerful technique to address bias: propensity score weighting (PSW), which applies weights to each subject instead of matching (or discarding) them.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score weighting. (read)

Kurz, C.F., Krzywinski, M. & Altman, N. (2025) Points of significance: Propensity score weighting. Nat. Methods 22:1–3.

Happy 2025 π Day—
TTCAGT: a sequence of digits

Thu 13-03-2025

Celebrate π Day (March 14th) and sequence digits like its 1999. Let's call some peaks.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2025 π DAY | TTCAGT: a sequence of digits. The digits of π are encoded into DNA sequence and visualized with Sanger sequencing. (details)

Crafting 10 Years of Statistics Explanations: Points of Significance

Sun 09-03-2025

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

Points of Significance is an ongoing series of short articles about statistics in Nature Methods that started in 2013. Its aim is to provide clear explanations of essential concepts in statistics for a nonspecialist audience. The articles favor heuristic explanations and make extensive use of simulated examples and graphical explanations, while maintaining mathematical rigor.

Topics range from basic, but often misunderstood, such as uncertainty and P-values, to relatively advanced, but often neglected, such as the error-in-variables problem and the curse of dimensionality. More recent articles have focused on timely topics such as modeling of epidemics, machine learning, and neural networks.

In this article, we discuss the evolution of topics and details behind some of the story arcs, our approach to crafting statistical explanations and narratives, and our use of figures and numerical simulations as props for building understanding.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Crafting 10 Years of Statistics Explanations: Points of Significance. (read)

Altman, N. & Krzywinski, M. (2025) Crafting 10 Years of Statistics Explanations: Points of Significance. Annual Review of Statistics and Its Application 12:69–87.

Propensity score matching

Mon 16-09-2024

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

In many experimental designs, we need to keep in mind the possibility of confounding variables, which may give rise to bias in the estimate of the treatment effect.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score matching. (read)

If the control and experimental groups aren't matched (or, roughly, similar enough), this bias can arise.

Sometimes this can be dealt with by randomizing, which on average can balance this effect out. When randomization is not possible, propensity score matching is an excellent strategy to match control and experimental groups.

Kurz, C.F., Krzywinski, M. & Altman, N. (2024) Points of significance: Propensity score matching. Nat. Methods 21:1770–1772.

Understanding p-values and significance

Tue 24-09-2024

P-values combined with estimates of effect size are used to assess the importance of experimental results. However, their interpretation can be invalidated by selection bias when testing multiple hypotheses, fitting multiple models or even informally selecting results that seem interesting after observing the data.

We offer an introduction to principled uses of p-values (targeted at the non-specialist) and identify questionable practices to be avoided.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Understanding p-values and significance. (read)

Altman, N. & Krzywinski, M. (2024) Understanding p-values and significance. Laboratory Animals 58:443–446.

Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentrePHSA
Google whack “vicissitudinal corporealization”
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