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π Day 2025 Art Posters - TTCAGT: a sequence of digits
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
2025 π DAY | TTCAGT: A sequence of digits. 768 digits of `\pi` as a Sanger sequencing trace of 1,536 peaks. Decode the sequence (BUY ARTWORK)

The art of Pi (`\pi`), Phi (`\phi`) and `e`


Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2024 π DAY | Explore the garden of digits.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2023 π DAY | Repeated sequence

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2022 π DAY | three one four: a number of digits

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2021 π DAY | Good things grow for those who wait.' edition.


Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2020 π DAY | The piku.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 π DAY | Hundreds of digits, hundreds of languages and a special kids' edition.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 π DAY | Street maps to new destinations.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 π DAY | Imagine the sky in a new way.


Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 π APPROXIMATION DAY | What would happen if about right was right.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 π DAY | These digits really fall for each other.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 π DAY | A transcendental experience.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π APPROXIMATION DAY | Spirals into roughness.


Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π DAY | Hypnotizes you into looking.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π DAY | Come into the fold.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 π DAY | Where it started.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
CIRCULAR π ART | And other distractions.

This section contains various art work based on `\pi`, `\phi` and `e` that I created over the years.

Some of the numerical art reveals interesting and unexpected observations. For example, the sequence 999999 in π at digit 762 called the Feynman Point. Or that if you calculate π to 13,099,586 digits you will find love.

`\pi` day art and `\pi` approximation day art is kept separate.

Count along ·
Like music with numbers? Try Angels at My Door (Una), Pt vs Ys (Yoshinori Sunahara), 2wicky (Hooverphonic), One (Aimee Mann), Straight to Number One (Touch and Go), 99 luftbaloons (Nena), and Aquarius (Boards of Canada)

The accidental similarity number (ASN) is a kind of overlap between numbers. I came up with this concept after creating typographical art about the `i`-ness of `\pi`.

Typography geek? If you like the geometry and mathematics of these posters, you may enjoy something more letter ed. Visions of type: Type Peep Show: The Private Curves of Letters posters.

The poster shows the accidental similarity number for `\pi`, `\phi` and `e`.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
The accidental similarity number for `\pi`, `\phi` and `e` created from the first 1,000,000 digits of each number. (posters, BUY ARTWORK)
news + thoughts

Happy 2025 π Day—
TTCAGT: a sequence of digits

Thu 13-03-2025

Celebrate π Day (March 14th) and sequence digits like its 1999. Let's call some peaks.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2025 π DAY | TTCAGT: a sequence of digits. The digits of π are encoded into DNA sequence and visualized with Sanger sequencing. (details)

Crafting 10 Years of Statistics Explanations: Points of Significance

Sun 09-03-2025

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

Points of Significance is an ongoing series of short articles about statistics in Nature Methods that started in 2013. Its aim is to provide clear explanations of essential concepts in statistics for a nonspecialist audience. The articles favor heuristic explanations and make extensive use of simulated examples and graphical explanations, while maintaining mathematical rigor.

Topics range from basic, but often misunderstood, such as uncertainty and P-values, to relatively advanced, but often neglected, such as the error-in-variables problem and the curse of dimensionality. More recent articles have focused on timely topics such as modeling of epidemics, machine learning, and neural networks.

In this article, we discuss the evolution of topics and details behind some of the story arcs, our approach to crafting statistical explanations and narratives, and our use of figures and numerical simulations as props for building understanding.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Crafting 10 Years of Statistics Explanations: Points of Significance. (read)

Altman, N. & Krzywinski, M. (2025) Crafting 10 Years of Statistics Explanations: Points of Significance. Annual Review of Statistics and Its Application 12:69–87.

Propensity score matching

Mon 16-09-2024

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

In many experimental designs, we need to keep in mind the possibility of confounding variables, which may give rise to bias in the estimate of the treatment effect.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score matching. (read)

If the control and experimental groups aren't matched (or, roughly, similar enough), this bias can arise.

Sometimes this can be dealt with by randomizing, which on average can balance this effect out. When randomization is not possible, propensity score matching is an excellent strategy to match control and experimental groups.

Kurz, C.F., Krzywinski, M. & Altman, N. (2024) Points of significance: Propensity score matching. Nat. Methods 21:1770–1772.

Understanding p-values and significance

Tue 24-09-2024

P-values combined with estimates of effect size are used to assess the importance of experimental results. However, their interpretation can be invalidated by selection bias when testing multiple hypotheses, fitting multiple models or even informally selecting results that seem interesting after observing the data.

We offer an introduction to principled uses of p-values (targeted at the non-specialist) and identify questionable practices to be avoided.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Understanding p-values and significance. (read)

Altman, N. & Krzywinski, M. (2024) Understanding p-values and significance. Laboratory Animals 58:443–446.

Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA
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