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My animation of 5 dimensions sets the stage for Max Cooper's track Ascent from his new album Unspoken Words.
Another mathy collaboration with Max!

Infinity with Max Cooper — In Six Minutes

Great fleas have little fleas upon their backs to bite ’em,
And little fleas have lesser fleas, and so ad infinitum.
And the great fleas themselves, in turn, have greater fleas to go on;
While these again have greater still, and greater still, and so on.
—Augustus de Morgan

1 · The story of infinity in 6 minutes

In collaboration with Max Cooper, we tell a story about infinity in 6 minutes (and 34 seconds).

What's the story about? Natural numbers, integers, rationals, reals, power sets and the cardinality of the continuum — a real visual parade of numbers.

But math is a serious matter — so we include two of Cantor's diagnoal proofs in the video. Watch as we show that the size of the set of rational numbers is the same as the set of natural numbers (making them countable) but that the size of the set of real numbers is larger (making them uncountable).

2 · Aleph 2 — Yearning for the Infinite

In science one tries to tell people,
in such a way as to be understood by everyone,
something that no one ever knew before.
But in poetry, it’s the exact opposite.
—Paul Dirac, Mathematical Circles Adieu by H. Eves [quoted]

The style of Aleph 2 is that of a low-fi terminal. We used the Classic Console font by Csaba Széll, which I extended to include more set theory symbols (download extended font).

The animation was closely synchronized to the music, all the while trying to avoid looking too much like something from the Matrix movie.

3 · Video walkthrough

To help you interpret what you are seeing, I walk you through the video and introduce you some advanced concepts of set theory. This way, next time you see an equation like `|\mathbb{R}| = | \mathbb{P}(\mathbb{N}) | = 2^{\aleph_0}`, you'll sprout a smile of joy.

Yearning for the Infinite - Max Cooper and Martin Krzywinski - Visualization of Infinity and Pi / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
We begin counting the natural numbers, whose cardinality is `|\mathbb{N}| = \aleph_0`. Screenshot from Max Cooper's Aleph 2 (Yearning for the Infinite). (Max Cooper/Martin Krzywinski)
Yearning for the Infinite - Max Cooper and Martin Krzywinski - Visualization of Infinity and Pi / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A bijection between the naturals and integers demonstrating that both have the same cardinality. Screenshot from Max Cooper's Aleph 2 (Yearning for the Infinite). (Max Cooper/Martin Krzywinski)
Yearning for the Infinite - Max Cooper and Martin Krzywinski - Visualization of Infinity and Pi / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A bijection between the naturals and rationals. We traversing the table of rationals in a zig-zag manner. Screenshot from Max Cooper's Aleph 2 (Yearning for the Infinite). (Max Cooper/Martin Krzywinski)
Yearning for the Infinite - Max Cooper and Martin Krzywinski - Visualization of Infinity and Pi / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
We alter the digits on the diagonal to create a real that is nowhere in the list. Screenshot from Max Cooper's Aleph 2 (Yearning for the Infinite). (Max Cooper/Martin Krzywinski)
Yearning for the Infinite - Max Cooper and Martin Krzywinski - Visualization of Infinity and Pi / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Power set elements of naturals (left) and reals (right). The size of these sets is separated by one step in the hierarchy of Aleph numbers, if the Continuum Hypothesis is true. Screenshot from Max Cooper's Aleph 2 (Yearning for the Infinite). (Max Cooper/Martin Krzywinski)
Yearning for the Infinite - Max Cooper and Martin Krzywinski - Visualization of Infinity and Pi / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Aleph remains. Screenshot from Max Cooper's Aleph 2 (Yearning for the Infinite). (Max Cooper/Martin Krzywinski)

These pages describe the system I build to generate the animation and the mathematics behind infinity, including sets, cardinality, countability, $\aleph$ and the Continuum Hypothesis.

I also present the animation system I built for the video, which was coded from scratch.

4 · My other collaborations with Max

If you like infinity, you might like dimensions too.

Check out my video for Max Cooper's Ascent, which animates 5-dimensional cubes doing their confusing things.

My animation of 5 dimensions sets the stage for Max Cooper's track Ascent from his new album Unspoken Words.
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Happy 2026 π Day—
Art for the 5%

Fri 13-03-2026

Celebrate π Day (March 14th) and enjoy the art — but only if you're part of the 5%.

Go ahead, see what you can't see.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2026 π DAY | Art for the 5%. Shown in the style of Ishihara color test plates, the art is visible only to those with colour blindness. (details)

Ishihara's Tests for Colour Deficiency

Sun 08-03-2026

Authentic and accurate images of Ishihara's test plates photographed (and lovingly color-corrected) from the 38-plate Ishihara's Tests for Colour Deficiency.

I also provide the position, size, and color of each circle on each test plate.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
ISHIHARA'S TEST PLATE 6 | This plate is part of the set of transformation plates. If you see 5, you're ok. If you see 2, you're not. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
ISHIHARA'S TEST PLATE 18 | This plate is part of the set of mysterious hidden plates. If you don't see anything, you're ok. If you see 5, you're not. (details)

Symmetric alternatives to the ordinary least squares regression

Wed 23-07-2025

What immortal hand or eye, could frame thy fearful symmetry? — William Blake, "The Tyger"

This month, we look at symmetric regression, which, unlike simple linear regression, it is reversible — remaining unaltered when the variables are swapped.

Simple linear regression can summarize the linear relationship between two variables `X` and `Y` — for example, when `Y` is considered the response (dependent) and `X` the predictor (independent) variable.

However, there are times when we are not interested (or able) to distinguish between dependent and independent variables — either because they have the same importance or the same role. This is where symmetric regression can help.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Symmetric alternatives to the ordinary least squares regression. Geometry of quantities minimized in OLS and symmetric regression. OLS minimizes `\Sigma e_y^2` in `Y` ~ `X` and `\Sigma e_x^2` `X` ~ `Y`. Pythagorean regression minimizes AB (magenta). Geometric means regression (GMR) minimizes area of ABP (orange). Orthogonal regression (OR) minimizes HP (blue). (read)

Luca Greco, George Luta, Martin Krzywinski & Naomi Altman (2025) Points of significance: Symmetric alternatives to the ordinary least squares regression. Nat. Methods 22:1610–1612.

Beyond Belief Campaign BRCA Art

Wed 11-06-2025

Fuelled by philanthropy, findings into the workings of BRCA1 and BRCA2 genes have led to groundbreaking research and lifesaving innovations to care for families facing cancer.

This set of 100 one-of-a-kind prints explore the structure of these genes. Each artwork is unique — if you put them all together, you get the full sequence of the BRCA1 and BRCA2 proteins.

Propensity score weighting

Mon 17-03-2025

The needs of the many outweigh the needs of the few. —Mr. Spock (Star Trek II)

This month, we explore a related and powerful technique to address bias: propensity score weighting (PSW), which applies weights to each subject instead of matching (or discarding) them.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score weighting. (read)

Kurz, C.F., Krzywinski, M. & Altman, N. (2025) Points of significance: Propensity score weighting. Nat. Methods 22:638–640.

Happy 2025 π Day—
TTCAGT: a sequence of digits

Thu 13-03-2025

Celebrate π Day (March 14th) and sequence digits like its 1999. Let's call some peaks.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2025 π DAY | TTCAGT: a sequence of digits. The digits of π are encoded into DNA sequence and visualized with Sanger sequencing. (details)
Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentrePHSA
Google whack “vicissitudinal corporealization”
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