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π Day 2025 Art Posters - TTCAGT: a sequence of digits
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
2025 π DAY | TTCAGT: A sequence of digits. 768 digits of `\pi` as a Sanger sequencing trace of 1,536 peaks. Decode the sequence (BUY ARTWORK)

`\pi` Day 2016 Art Posters


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2024 π DAY | Explore the garden of digits.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2023 π DAY | Repeated sequence

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2022 π DAY | three one four: a number of digits

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2021 π DAY | Good things grow for those who wait.' edition.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2020 π DAY | The piku.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 π DAY | Hundreds of digits, hundreds of languages and a special kids' edition.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 π DAY | Street maps to new destinations.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 π DAY | Imagine the sky in a new way.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 π APPROXIMATION DAY | What would happen if about right was right.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 π DAY | These digits really fall for each other.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 π DAY | A transcendental experience.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π APPROXIMATION DAY | Spirals into roughness.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π DAY | Hypnotizes you into looking.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 π DAY | Come into the fold.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 π DAY | Where it started.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
CIRCULAR π ART | And other distractions.

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Most of the art is available for purchase as framed prints and, yes, even pillows. Sleep's never been more important — I take custom requests.

This year's `\pi` day art collection celebrates not only the digit but also one of the fundamental forces in nature: gravity.

In February of 2016, for the first time, gravitational waves were detected at the Laser Interferometer Gravitational-Wave Observatory (LIGO).

The signal in the detector was sonified—a process by which any data can be encoded into sound to provide hints at patterns and structure that we might otherwise miss—and we finally heard what two black holes sound like. A buzz and chirp.

The art is featured in the Gravity of Pi article on the Scientific American SA Visual blog.

this year's theme music

All the art was processed while listening to Roses by Coeur de Pirate, a brilliant female French-Canadian songwriter, who sounds like a mix of Patricia Kaas and Lhasa. The lyrics Oublie-moi (Forget me) are fitting with this year's theme of gravity.

Mais laisse-moi tomber, laisse-nous tomber
Laisse la nuit trembler en moi
Laisse-moi tomber, laisse nous tomber
Cette fois

But let me fall, let us fall
Let the night tremble in me
Let me fall, let us fall
This time

The art is generated by running a simulation of gravity in which digits of `\pi` are each assigned a mass and allowed to collide eand orbit each other.

The mathematical details of the simulation can be found in the code section.

exploring force of gravity in `\pi`

A simulation starts with taking `n` digits of `\pi` and arranging them uniformly around a circle. The mass of each digit, `d_i` (e.g. 3), is given by `(1+d)^k` where `k` is a mass power parameter between 0.01 and 1. For example, if `k=0.42` then the mass of 3 is `(1+3)^{0.42} = 1.79`.

collapsing three digits—3.14 collide

The figure below shows the evolution of a simulation with `n=3` digits and `k=1`. The digits 3 and 4 collide to form the digit `3+4 = 7` and immediately collides with 1 to form `7+1=8`. With only one mass left in the system, the simulation stops.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The evolution of a simulation of gravity using `n=3` digits of `\pi` and the mass power `k=1`. The masses are initialized with zero velocity. (zoom)

adding initial velocity to each mass

When masses have initial velocities, the patterns quickly start to get interesting. In the figure above, the masses are initalized with zero velocity. As soon as the simulation, each mass immediately starts to move directly towards the center of mass of the other two masses.

When the initial velocity is non-zero, such as in the figure below, the masses don't immediately collapse towards one another. The masses first travel with their initial velocity but immediately the gravitational force imparts acceleration that alters this velocity. In the examples below, only those simulations in which the masses collapsed within a time cutoff are shown.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The evolution of a simulation of gravity using `n=3` digits of `\pi` and the mass power `k=1` in which all masses collapsed. The masses are initialized with a random velocity. (zoom)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The evolution of 16 simulations of gravity using `n=3` digits of `\pi` and the mass power `k=1` in which all masses collapsed. The masses are initialized with a random velocity. (zoom)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The evolution of 49 simulations of gravity using `n=3` digits of `\pi` and the mass power `k=1` in which all masses collapsed. The masses are initialized with a random velocity. (zoom)

allowing the simulation to evolve

Depending on the initial velocities, some systems collapse very quickly, which doesn't make for interesting patterns.

For example, the simulations above evolved over 100,000 steps and in some cases the masses collapsed within 10,000 steps. In the figure below, I require that the system evolves for at least 15,000 steps before collapsing. Lovely doddles, don't you think?


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The evolution of 36 simulations of gravity using `n=3` digits of `\pi` and the mass power `k=1` in which all masses collapsed after a minimum amount of time. The masses are initialized with a random velocity. (zoom)

exploring ensembles

When a simulation is repeated with different initial conditions, the set of outcomes is called an ensemble.

Below, I repeat the simulation 100 times with `n=3` and `k=0.2`, each time with slightly different initial velocity. The velocities have their `x`- and `y`-components normally distributed with zero mean and a fixed variance. Each of the four ensembles has its simulations evolve over progressively more time steps: 5,000, 7,500, 10,000, and 20,000.

You can see that with 5,000 steps the masses don't yet have a chance to collide. After 7,500, there have been collisions in a small number of systems. The blue mass corresponds to the 3 colliding with 4 and the green mass to 1 colliding with 4. After 10,000, even more collisions are seen and in 3 cases we see total collapse (all three digits collided). After 20,000,


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The evolution of 100 simulations of gravity over total time `t` using `n=3` digits of `\pi` and the mass power `k=0.2`. Within each ensemble, the masses are initialized with a different random velocity in each instance. (zoom)

varying masses

The value of `k` greatly impacts the outcome of the simulation. When `k` is very small, all the digits have essentially the same mass. For example, when `k=0.01` the 0 has a mass of 1 and 9 has a mass of 1.02.

When `k` is large, the difference in masses is much greater. For example, for `k=2` the lightest mass is `(1+0)^2=1` and the heaviest `(1+9)^2=10`. Because the acceleration of a mass is proportional to the mass that is attracting it, in a pair of masses the light mass will accelerate faster.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Larger values of `k` create greater diversity among the masses. Shown are simulations of 36 digits with `k` values varying from 0.1 to 3. The total mass of the system, `\Sigma m`, is also shown.`. (zoom)

increasing number of masses

As the number of digits is increased, the pattern of collapse doesn't qualitatively change.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Simulations for `n = 50, 100, 250` and `500` masses with `k = 0.5`. (zoom)

gravity makes beautiful doodles

I ran a large number of simulations. For various values of `n` and `k`, I repeated the simulation several times to sample different intial velocities.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Thumbnails of `\pi` digit orbital simulations for various values of `n` and `k`. (zoom)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gravitational attraction paths of the first 100 digits of `\pi` for `k = 0.3`, `0.6` and `0.8` with initial velocities randomly set. Three instances of the simulation are shown, each with different intital velocities. (zoom)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gravitational attraction paths of the first 60 digits of `\pi` for `k = 1`. After 100,000 time steps, some masses are still orbiting within the canvas (e.g. green mass at bottom right). The numbers next to the masses correspond to the digits (those around the circle are the first 50 digits of `\pi` and others are the sum (mod 10) of digits that collided). Also shown next to the numbers is their mass, index and indices of masses that formed them. (zoom)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gravitational attraction paths of the first 50 digits of `\pi` for `k = 0.4`. The numbers next to the masses correspond to the digits (those around the circle are the first 50 digits of `\pi` and others are the sum (mod 10) of digits that collided). (zoom)

Below is a great example of how a stable orbital pattern of a pair of masses can be disrupted by the presence of another mass. You can see on the left that once the light red mass moves away from the orange/green pair, they settle into a stable pattern.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gravitational attraction paths of the first 50 digits of `\pi` for `k = 0.9`. The numbers next to the masses correspond to the digits (those around the circle are the first 50 digits of `\pi` and others are the sum (mod 10) of digits that collided). (zoom)

The figure below shows one of my favourite patterns. As the digits collide, three masses remain, which leave the system. They remain under each other's gravitational influence, but are moving too quickly to return to the canvas within the time of the simulation.


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gravitational attraction paths of the first 90 digits of `\pi` for `k = 0.8`. The digits collide, leaving three rapidly-moving masses, which leave the canvas. (zoom)

how the idea developed

interactive gravity simulator

Use this fun inteactive gravity simulator if you want to drop your own masses and watch them orbit.

news + thoughts

Beyond Belief Campaign BRCA Art

Wed 11-06-2025

Fuelled by philanthropy, findings into the workings of BRCA1 and BRCA2 genes have led to groundbreaking research and lifesaving innovations to care for families facing cancer.

This set of 100 one-of-a-kind prints explore the structure of these genes. Each artwork is unique — if you put them all together, you get the full sequence of the BRCA1 and BRCA2 proteins.

Propensity score weighting

Mon 17-03-2025

The needs of the many outweigh the needs of the few. —Mr. Spock (Star Trek II)

This month, we explore a related and powerful technique to address bias: propensity score weighting (PSW), which applies weights to each subject instead of matching (or discarding) them.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score weighting. (read)

Kurz, C.F., Krzywinski, M. & Altman, N. (2025) Points of significance: Propensity score weighting. Nat. Methods 22:1–3.

Happy 2025 π Day—
TTCAGT: a sequence of digits

Thu 13-03-2025

Celebrate π Day (March 14th) and sequence digits like its 1999. Let's call some peaks.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2025 π DAY | TTCAGT: a sequence of digits. The digits of π are encoded into DNA sequence and visualized with Sanger sequencing. (details)

Crafting 10 Years of Statistics Explanations: Points of Significance

Sun 09-03-2025

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

Points of Significance is an ongoing series of short articles about statistics in Nature Methods that started in 2013. Its aim is to provide clear explanations of essential concepts in statistics for a nonspecialist audience. The articles favor heuristic explanations and make extensive use of simulated examples and graphical explanations, while maintaining mathematical rigor.

Topics range from basic, but often misunderstood, such as uncertainty and P-values, to relatively advanced, but often neglected, such as the error-in-variables problem and the curse of dimensionality. More recent articles have focused on timely topics such as modeling of epidemics, machine learning, and neural networks.

In this article, we discuss the evolution of topics and details behind some of the story arcs, our approach to crafting statistical explanations and narratives, and our use of figures and numerical simulations as props for building understanding.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Crafting 10 Years of Statistics Explanations: Points of Significance. (read)

Altman, N. & Krzywinski, M. (2025) Crafting 10 Years of Statistics Explanations: Points of Significance. Annual Review of Statistics and Its Application 12:69–87.

Propensity score matching

Mon 16-09-2024

I don’t have good luck in the match points. —Rafael Nadal, Spanish tennis player

In many experimental designs, we need to keep in mind the possibility of confounding variables, which may give rise to bias in the estimate of the treatment effect.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Propensity score matching. (read)

If the control and experimental groups aren't matched (or, roughly, similar enough), this bias can arise.

Sometimes this can be dealt with by randomizing, which on average can balance this effect out. When randomization is not possible, propensity score matching is an excellent strategy to match control and experimental groups.

Kurz, C.F., Krzywinski, M. & Altman, N. (2024) Points of significance: Propensity score matching. Nat. Methods 21:1770–1772.

Understanding p-values and significance

Tue 24-09-2024

P-values combined with estimates of effect size are used to assess the importance of experimental results. However, their interpretation can be invalidated by selection bias when testing multiple hypotheses, fitting multiple models or even informally selecting results that seem interesting after observing the data.

We offer an introduction to principled uses of p-values (targeted at the non-specialist) and identify questionable practices to be avoided.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Understanding p-values and significance. (read)

Altman, N. & Krzywinski, M. (2024) Understanding p-values and significance. Laboratory Animals 58:443–446.

Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentrePHSA
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